Effectiveness of Therapy Topical Binahong Leaf Extract in Modern Wound Care for Healing Diabetic Wounds in Modern Wound Care Homes Husada Prima Mandiri Mojokerto

  • Raras Merbawani School of health Bina Sehat PPNI Mojokerto Indonesia
  • Nonse Hasan Ragil Saputri School of health Bina Sehat PPNI Mojokerto Indonesia
  • asef wildan munfadlila STIKES BINA SEHAT PPNI MOJOKERTO
Keywords: Keywords: Binahong Leaf Extract, Diabetic Wounds, Modern Wound Care


One of the diabetes mellitus syndromes is diabetic wounds. Diabetic wound treatment is good for preventing infection and amputation. Treatment of wounds that can heal wounds and develop at this time is modern wound care using topical therapy / modern clothing, where expensive costs require care that requires a large cost. Plants that can be used to heal wounds are leaves of binahong because they contain flavonoids, oleanolic acid, protein, ascorbic acid. and saponins. This study aims to determine topical treatment of leaf extract in modern treatments to treat diabetic wounds. The design of this study was a quasi experiment with a non equivalent control group design. The population in this study were people with diabetes mellitus with diabetic wounds at 34 Modern Husada Prima Mandiri Wound Care Homes. The sampling technique is consecutive sampling with a sample of 32 people. Data collection uses MANUAL BWAT. The results showed that the average score was lowest for groups (7.69 <8.00). The results of the analysis of researchers in groups were effective and effective diabetic wounds. This is because there are differences that are on average not too good for the second group (Difference 0.31). In addition, the average GDA, vascularization conditions and losses in the groups were worse with the control groups, where they could affect the wound. Ascorbic acid content and protein in binahong leaf extract help grow granulation tissue, support granulation tissue and accelerate epithelialization.


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Amertha, IBPM, S Soeliongan, and C Kountul. 2012. “In Vitro Inhibition Zone Test of Bihanong (Anredera Cordifolia) towards Staphylococcus Aureus, Enterococcus Faecalis, Escherichia Coli, and Pseudomonas Aeruginosa.†Indonesia Journal of Biomedical Science.

Baroni, Adone et al. 2012. “Structure and Function of the Epidermis Related to Barrier Properties.†Clinics in Dermatology.

Botusan, I. R. et al. 2008. “Stabilization of HIF-1 Is Critical to Improve Wound Healing in Diabetic Mice.†Proceedings of the National Academy of Sciences.

Chattopadhyay, Sayani, and Ronald T. Raines. 2014. “Review Collagen-Based Biomaterials for Wound Healing.†Biopolymers.

Chung, Kwanghun, and Karl Deisseroth. 2013. “CLARITY for Mapping the Nervous System.†Nature Methods.

Complications, Diabetes-related. 2008. “Diabetes-Related Complications.†Physical Therapy.

Departemen Kesehatan Republik Indonesia. 2013. “Laporan Hasil Riset Kesehatan Dasar (RISKESDAS) 2013.†Laporan Nasional 2013.

Fantin, Alessandro et al. 2010. “Tissue Macrophages Act as Cellular Chaperones for Vascular Anastomosis Downstream of VEGF-Mediated Endothelial Tip Cell Induction.†Blood.

Foldes, Eugene. 1947. “Diabetes and Hypertension.†The American Journal of Medicine.

Kartika, Gde Raka Angga, Sri Andayani, and Soelistyowati Soelistyowati. 2016. “Potensi Ekstrak Daun Binahong (Anredera Cordifolia) Sebagai Penghambat Bakteri Vibrio Harveyi.†Journal of Marine and Aquatic Sciences.

Miladiyah, Isnatin, and Bayu Rizky Prabowo. 2012. Universa Medica Ethanolic Extract of Anredera Cordifolia (Ten.) Steenis Leaves Improved Wound Healing in Guinea Pigs.

Nie, Chunlei et al. 2011. “Locally Administered Adipose-Derived Stem Cells Accelerate Wound Healing through Differentiation and Vasculogenesis.†Cell Transplantation.

Oliver, N. S., C. Toumazou, A. E.G. Cass, and D. G. Johnston. 2009. “Glucose Sensors: A Review of Current and Emerging Technology.†Diabetic Medicine.

Organization, World Health. 2014. “WHO | Noncommunicable Diseases Country Profiles 2014.†WHO.

Pereira, Rúben F., and Paulo J. Bártolo. 2016. “Traditional Therapies for Skin Wound Healing.†Advances in Wound Care.

Reinke, J. M., and H. Sorg. 2012. “Wound Repair and Regeneration.†European Surgical Research.

Sarah, W et al. 2004. “Global Prevalence of Diabetes.†Diabetes care.

Selawa, W, MRJ Runtuwene, and G Citraningtyas. 2013. “Kandungan Flavonoid Dan Kapasitas Antioksidan Total Ekstrak Etanol Daun Binahong [Anredera Cordifolia(Ten.)Steenis.].†Pharmacon.

Shah, Jayesh. 2010. “Hyperbaric Oxygen Therapy.†Journal of the American College of Certified Wound Specialists.

Zamboni, William A., Leslie K. Browder, and John Martinez. 2003. “Hyperbaric Oxygen and Wound Healing.†Clinics in Plastic Surgery.

How to Cite
Merbawani, R., Ragil Saputri, N., & munfadlila, asef. (2019). Effectiveness of Therapy Topical Binahong Leaf Extract in Modern Wound Care for Healing Diabetic Wounds in Modern Wound Care Homes Husada Prima Mandiri Mojokerto. INTERNATIONAL JOURNAL OF NURSING AND MIDWIFERY SCIENCE (IJNMS), 2(03), 234-243. https://doi.org/10.29082/IJNMS/2018/Vol2/Iss03/179